CHRETIEN Denis

  • Université de Rennes 1
    UMR6026 Interactions Cellulaires et Moléculaires
    Equipe Tubulin and Interacting Proteins
    Campus de Beaulieu, Bât. 13
    35042 RENNES Cedex
    FRANCE

  • Phone: + 33 (0)2 23 23 67 64
  • Fax+ 33 (0)2 23 23 50 52
  • Email adress:
  • Published by: Denis CHRETIEN
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Publications

  • Trehalose prevents aggregation of exosomes and cryodamage
    Bosch S., de Beaurepaire L., Allard M., Mosser M., Heichette C., Chrétien D., Jegou D., and J.-M. Bach Scientific Reports, 2016, 6:36162.
    Scientific Reports
    - SharedIt

  • EB1 interacts with outwardly curved and straight regions of the microtubule lattice
    Guesdon A., Bazile F., Buey R.M., Mohan R., Monier S., Rodríguez García R., Angevin M., Heichette C., Wieneke R., Tampé R., Duchesne L., Akhmanova A., Steinmetz M.O., and D. Chrétien
    Nature Cell Biology, 2016, Sept 12
    Pubmed - Springer Nature Sharing

  • Hsp90 directly interacts, in vitro, with amyloid structures and modulates their assembly and disassembly
    Schirmer C., Lepvrier E., Duchesne L., Decaux O., Thomas D., Delamarche C., and C. Garnier.
    Biochimica et Biophysica Acta, 2016 1860:2598-609.
    Pubmed

  • The formation of ordered nanoclusters controls cadherin anchoring to actin and cell–cell contact fluidity
    Strale P.O., Duchesne L., Peyret G. Montel L., Nguyen T., Png E, Tampé R., Troyanovsky S., Hénon S., Ladoux B., and R.M. Mège.
    The Journal of Cell Biology, 2015, 210:333-346.
    JCB

  • Conditional Random Fields for tubulin-microtubule segmentation in cryo-electron tomography
    Kervrann C., Blestel S., and D. Chrétien
    Proceedings of the IEEE International Conference on Image Processing (ICIP 2014), Paris, Pages 1-4,  October 2014

  • Ensconsin/Map7 promotes microtubule growth and centrosome separation in Drosophila neural stem cells
    Gallaud E., Caous R., Pascal A., Bazile F., Gagné J-P., Huet S., Poirier G. G., Chrétien D., Richard-Parpaillon L., and R. Giet
    The Journal of Cell Biology, 2014, 204:1111-1121.
    Weblink

  • Single versus dual-axis cryo-electron tomography of microtubules assembled in vitro: Limits and perspectives
    Guesdon A., Blestel S., Kervrann C. and D. Chrétien
    Journal of Structural Biology, 2013, 1:169-178.
    Weblink

  • Transport of Fibroblast Growth Factor 2 in the Pericellular Matrix Is Controlled by the Spatial Distribution of Its Binding Sites in Heparan Sulfate
    Duchesne L., Octeau V., Bearon R.N., Beckett A., Prior I., Lounis B., and D.G. Fernig
    PLoS Biology, 2012, 10, e1001361.
    Weblink

  • TubuleJ
    Blestel S., Guesdon A., Kervrann C. and D. Chrétien
    IDDN.FR.001.240023.000.S.P.2011.000.21000
    APP

  • Cryo-electron tomography of microtubules assembled in vitro from purified components
    Coquelle F., Blestel S., Heichette C., Arnal I., Kervrann C. and D. Chrétien
    Methods in Molecular Biology, 2011, 777:193-208.
    Pubmed

  • GDP-tubulin incorporation into growing microtubules modulates polymer stability
    Valiron, O., Arnal, I., Caudron, N., and D. Job
    The Journal of Biological Chemistry, 2010, 285:17507-13.
    Pubmed

  • Procentriole assembly revealed by cryo-electron tomography
    Guichard, P., Chrétien, D., Marco, S., and A.-M. Tassin
    The Embo Journal, 2010, 29:1565-72.
    Pubmed

  • The 90-kDa heat shock protein HSP90 protects tubulin against thermal denaturation
    Weis, F., Moullintraffort, L., Heichette, C., Chrétien, D., and C. Garnier
    The Journal of Biological Chemistry
    , 2010, 285:9525-34.
    Pubmed

  • Mercury (Drosophila Tubulin Binding Cofactor B) controls cell polarity through the stabilisation of the microtubule network
    Baffet, A., Benoit, B., Gourhand, V., Heichette, C., Chrétien, D., and A. Guichet
    Mechanisms of Development, 2009, 126:S147-S148.
    Pubmed

  • Small and Stable Peptidic PEGylated Quantum Dots to Target Polyhistidine-Tagged Proteins with Controlled Stoichiometry
    Dif A., F. Boulmedais, M. Pinot, V. Roullier, M. Baudy-Floc'h, F.M. Coquelle, S. Clarke, P. Neveu, F. Vignaux, R. Le Borgne, M. Dahan, Z. Gueroui, and V. Marchi-Artzner
    Journal of the American Chemical Soc
    iety
    , 2009, 131:14738-46.
    Pubmed

  • Structural basis of EB1 effects on microtubule dynamics
    Coquelle, F.M
    ., Vitre, B., and I. Arnal
    Biochemical Society Transactions
    , 2009, 37:997-1001.
    Pubmed

  • A Fourier-based method for detecting curved microtubule centers: Application to straightening of cryo-electron microscope images
    Blestel, S., Kervrann, C., and D. Chrétien
    Proceedings of the IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2009. pp. 298-301.
    Web link

  • Second harmonic microscopy of axonemes
    Odin, C., Heichette, C., Chrétien,D., and Y. Le Grand
    Optics Express, 2009, 17:9235–9240.
    Pubmed PDF (1.2 MB)

  • Effects of confinement on the self-organization of microtubules and motors
    Pinot, M., Chesnel, F., Kubiak, J. Z., Arnal, I., Nedelec, F.J. and Z. Gueroui
    Current Biology, 2009, 19:954-960.
    Pubmed

  • Complex relationship between TCTP, microtubules and actin microfilaments regulates cell shape in normal and cancer cells
    Bazile F., Pascal A., Arnal I., Le Clainche C., Chesnel F. and J.Z. Kubiak
    Carcinogenesis
    , 2009,
    30:555-565.
    Pubmed

  • EB1 regulates microtubule dynamics and tubulin sheet closure in vitro
    Vitre, B., Coquelle, F. M., Heichette, C., Garnier, C., Chrétien, D. and I. Arnal
    Nature Cell Biology, 2008, 10:415-421.
    Pubmed

  • Vitrification of dynamic microtubules
    Arnal, I., Malleter, M. and D. Chrétien
    In " Handbook of Cryopreparation Methods for Electron Microscopy"
    Cavalier, A., Spehner, D. and B.M. Hembel editors. 2008, CRC Press.
    Web link

  • Visualization of cell microtubules in their native state
    Bouchet-Marquis, C., Zuber, B., Glynn, A. M., Eltsov, M., Grabenbauer, M., Goldie, K. N., Thomas, D., Frangakis, A. S., Dubochet, J. and D. Chrétien
    Biology of the Cell, 2007, 99:45-53
    PubMed
    Cover

  • Why is the microtubule lattice helical?
    Hunyadi, V., Chrétien, D., Flyvbjerg, H. and I. M. Jánosi
    Biology of the Cell, 2007, 99:117-128
    PubMed, Cover 

  • Water-soluble pegylated quantum dots: from a composite hexagonal phase to isolated micelles
    Boulmedais, F., Bauchat, P., Brienne, M. J., Arnal, I., Artzner, F., Gacoin, T., Dahan, M. and V. Marchi-Artzner
    Langmuir, 2006, 22:9797-9803
    PubMed

  • Global and local control of microtubule destabilization promoted by a catastrophe kinesin MCAK/XKCM1
    Kinoshita, K., Noetzel, T. L., Arnal, I., Drechsel, D. N. and A. A. Hyman
    Journal of Muscle Research and Cell Motility, 2006, 27:107-114
    PubMed

  • Mechanical stress induced mechanism of microtubule catastrophes
    Hunyadi, V., Chrétien, D. and I. M. Jánosi
    Journal of Molecular Biology, 2005, 348:927-938
    PubMed

  • CLIP-170/tubulin-curved oligomers coassemble at microtubule ends and promote rescues
    Arnal, I., Heichette, C., Diamantopoulos, G. S. and D. Chrétien
    Current Biology, 2004, 14:2086-2095
    PubMed

  • Dynamique du fuseau : vers une cible anti-cancéreuse
    Arnal, I., Sassoon, I. and R. Tournebize
    Médecine et Science, 2002, 18:1227-1235
    PDF (371 Ko)

  • Microtubule nucleation from stable tubulin oligomers
    Caudron, N., Arnal, I., Buhler, E., Job, D. and O. Valiron
    The Journal of Biological Chemistry, 2002, 277:50973-50979
    PubMed html PDF (332 Ko)

  • Structural microtubule cap: stability, catastrophe, rescue, and third state
    Jánosi, I. M., Chrétien, D. and H. Flyvbjerg
    Biophysical Journal, 2002, 83:1317-1330
    PubMed html PDF (510 Ko)

  • Microtubules switch occasionally into unfavorable configurations during elongation
    Chrétien, D. and S. D. Fuller
    Journal of Molecular Biology, 2000, 298:663-676
    PubMed